Grapefruit Juice and Kratom: Why They Make a Great Combination

Medically reviewed by — Research analysis by Alex Eriksson

Grapefruit juice and kratom is a mix that’s often recommended by enthusiasts of this fascinating herb. And surely, you’re wondering why this is the case.

Well, there are two advantages to mixing kratom with grapefruit. The funny thing is, most users recognize either one of these advantages and completely overlook the other for whatever reason.

Grapefruit Juice and Kratom: Two Great Perks

The first reason why kratom is mixed with white grapefruit juice (or any kind of grapefruit juice) is because of the latter’s potentiating effects. It’s actually one of the most popular kratom potentiators out there.

By using pregnenolone cream or pregnenolone supplements, the levels of the compound in the body increases, and this brings about various benefits such as fatigue relief, and delay of the aging process.

The secret behind grapefruit’s potentiating ability lies in its citric acid content. The alkaloids present in kratom are soluble in citric acid, which is also present in other fruit products such as orange juice and cranberry juice.

Because of this solubility, the alkaloids found in kratom become more readily available, which in effect boosts potency. This is why adding grapefruit juice in preparations such as kratom tea makes a lot of sense.

The second reason why kratom is mixed with grapefruit juice is simply because it helps improve taste. The flavor of grapefruit is a great foil to the slightly bitter taste of kratom.

Cat's claw and other similar Chinese herbs may serve as additional potentiators. Lion's mane mushroom, despite being recommended by some, doesn’t really enhance kratom’s potency but rather works by improving immunity and overall health.

Preparing the Mix

Blending kratom with grapefruit juice is actually a very simple thing. All you have to do is mix a good amount of grapefruit juice with kratom powder or tea.

Within a few minutes after mixing, the alkaloids found in kratom will be extracted, meaning more of it will be available for your benefit—and of course, enjoyment.

The most popular way of consuming this kratom-grapefruit combination is, well, to drink it. However, there are some enthusiasts who mix it with vape oil and smoke the resulting concoction through their vape pens.

Whether you choose to drink it or smoke it depends on your personal preference. Regardless, using grapefruit to potentiate kratom is a proven technique.

While there’s no specific ratio to worry about when it comes to combining grapefruit and kratom, you’ll still have to be careful with your approach. If possible, switch between kratom strains to avoid developing tolerance.

Likewise, if you’re sensitive to a relatively high dose of kratom, don’t just mix in the usual amount you’re taking. A smaller portion might provide the same anti-anxiety, pain-relieving kratom effects, given grapefruit’s potency-enhancing capacity.

A Word of Caution

While both kratom and grapefruit are safe to consume both individually and as a combination, there are specific interactions that you should watch out for, especially if you are taking medications.

The furanocoumarins found in grapefruit juice are known to inhibit certain enzymes in your liver. This could prevent the breakdown of a drug in your body, causing it to stay active for far too long.

At the same time, grapefruit juice can also decrease the potency of specific drugs. The mechanism behind this phenomenon is not yet well-understood and considered by experts as possibly multi-factorial.

Potency and Flavor

There’s no denying that grapefruit juice and kratom is an excellent combination. It makes your kratom preparation more powerful, all while improving flavor.

Alex Eriksson (Research Analysis)

Alex Eriksson is the founder of Epic Kratom, a blog dedicated to all Kratom lovers that provide honest and research-backed advice on how people can treat their chronic health problems using Kratom.

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